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Solutions that deviate significantly from this range cause irritation and may trigger excessive mucus secretion that impairs absorption

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doi: 10.1097/AOG.0b013e3181ed721d

Pretreatment of capsaicin reduces the levels of pro-inflammatory cytokines IL-1 and IL-6 in brain tissue stimulated by ibotenate, and inhibits the activity of brain mast cells in a dose-dependent manner [193]

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